How It Works

/How It Works
How It Works 2019-01-03T08:12:13+00:00


Does your horse or small animal suffer from respiratory problems, such as allergies, airway irritation, inflammation and infections?

Would the performance and comfort improve with clearer airways?


Nebulisation is a treatment technique in which tiny spherical droplets of aerosolised drugs are generated and inhaled by the patient. The droplets then shower out at various levels of the respiratory tract, depending on their size. It is the size of the droplets that are generated by Flexineb that make the equine and small animal nebulisations systems so effective.

Medication delivery is so important because many airway diseases involve the lower airway, which cannot be properly treated if the size of the nebulised particle is too large to reach the small airways deep in the lung.  To reach the lower airway the particle size needs to be between 1 to 5 microns in diameter, and this is where the technology of Flexineb creates the particle size necessary to treat the lower respiratory system.


The Flexineb aerosol generator technology, converts liquids into a fine aerosol for inhalation into the lungs of a horse or small animal. An important component of this technology is the medication cup, which incorporates a wafer thin metallic membrane with micro holes. It is a high quality alloy and the vibration of this membrane that acts like a micro pump and converts the liquid into a fine aerosol.

Extensive testing conducted by an independent laboratory on Flexineb shows 71% of the medication inhaled is 5 microns or less, which means 71% of the drug will reach the lower airways. With the use of scintigraphy (see attached document) it is clear that the lung field achieves full exposure to the medication.

The Flexineb Controller also includes an Automatic Tuning (AMT) Feature, whereby the system automatically scans every 30 seconds to determine the optimum operating point.


The medication cup & drug combination choice can have a big impact on the delivery time and aerosol droplet size.

A GREY labelled cup used with high viscosity oily type drugs can lead to slow delivery or failure to nebulise.

A GREEN labelled cup used with low viscosity watery type drugs can lead to very fast delivery and the generation of big aerosol droplets leading to pools of medication wasted in the bottom of the mask chamber.

A BLUE labelled cup used with low viscosity watery type drugs will nebulise but the delivery time will be slow. It is not suitable for high viscosity oily type drugs.

Please refer to the medication chart which will guide you to choose the correct cup for the medication you wish to use.

Further Information

Flexineb E2 Medication Chart (download pdf)


There is only one medication cup for Flexineb C1 (Small Animal) which is designed to be used with a wide range of medications and solutions (refer to the medication chart) The medication cup will hold 6ml of liquid but is expandable to 24ml using a plug in extension
cup accessory. The controller has a 5 minute timer function therefore if the extension cup is used the controller will need to be re-started to complete the dose.


The medication cups for the equine and small animal nebulisers are a wearing part. On average these cups will deliver 150 treatments. Correct cleaning will promote the life of the medication cup (refer to the cleaning instructions).